Chemical transformations of vitamin B2 in aquatic systems

Authors

DOI:

https://doi.org/10.52673/18570461.25.3-78.07

Keywords:

photolysis, aquatic systems, redox state, vitamin B2

Abstract

This paper is devoted to the study of the chemical transformations of vitamin B2 (riboflavin) in aquatic systems and its impact on the chemical self-purification processes of natural waters. The kinetics of the processes were monitored based on the vitamin concentration, determined by a direct spectrophotometric method at a wavelength of 444 nm. The research results demonstrated that under natural water conditions, vitamin B2 is stable, does not undergo oxidation by dissolved oxygen and hydrogen peroxide, and does not remove Cu(II) ions from their hydrochemical cycle by forming complex compounds. At the same time, riboflavin undergoes direct photolysis and generates reactive oxygen species, a phenomenon that has a positive impact on the self-purification processes and the redox state of the waters.

References

1. Averianova, L.; Balabanova, L.; Son, O.; Podvolotskaya, A. Production of vitamin B2 (Riboflavin) by microorganisms: an overview. In: Frontiers in Bioengineering and Biotechnology, 2020, nr. 8:570828, 23, https://doi.org/10.3389/fbioe.2020.570828

2. Sánchez-Machado, D.I.; López-Cervantes, J.; López-Hernández, J.; Paseiro-Losada P. Simultaneous determination of thiamine and riboflavin in edible marine seaweeds by high-performance liquid chromatography. In: Journal of Chromatographic Science, 2004, vol. 42(3), 117-120, https://doi.org/10.1093/chromsci/42.3.117

3. Revuelta, J.; Ledesma-Amaro, R.; Jiménez, A. Industrial production of vitamin B2 by microbial fermentation. In: Industrial biotechnology of vitamins, biopigments, and antioxidants, 2016, 15-40, https://doi.org/10.1002/9783527681754.ch2

4. You, J.; Pan, X.; Yang, C.; Du, Y.; Osire, T.; Yang, T. Microbial production of riboflavin: Biotechnological advances and perspectives. In: Metabolic Engineering, 2021, 68, 46-58, https://doi.org/10.1016/j.ymben.2021.08.009

5. Schwechheimer, S.; Park, E.; Revuelta, J.; Becker, J.; Wittmann, C. Biotechnology of riboflavin. In: Applied Microbiology and Biotechnology, 2016, 100(5), 2107-2119, https://doi.org/10.1007/s00253-015-7256-z

6. Ahmad, I.; Fasihullah, Q.; Noor, A.; Ansari, I.; Ali, Q. Photolysis of riboflavin in aqueous solution: a kinetic study. In: International Journal of Pharmaceutics, 2004, nr. 280, 199-208, https://doi.org/10.1016/j.ijpharm.2004.05.020

7. Jazzar, M.M.; Naseem, I. Genotoxicity of photoilluminated riboflavin in the presence of Cu(II). In: Free Radical Biology & Medicine, 1996, vol. 21, no. 1, 7-14, https://doi.org/10.1016/0891-5849(95)02156-6

8. Naseem, I.; Ahmed, M.S.; Bhat, R.; Hadi, S.M. Cu(II)-Dependent degradation of DNA by riboflavin. In: Food and Chemical Toxicology, 1993, vol. 31(8), 589-597, https://doi.org/10.1016/0278-6915(93)90209-H

9. European pharmacopoeia, 11th Edition, 2023, p. 3882.

10. Masłowska, J.; Malicka, M. Thermal decompositions of complexes of metal ions with riboflavin. In: Journal of Thermal Analysis and Calorimetry, 1987, vol. 32(6), 1659-1665, https://doi.org/10.1007/BF01913943

11. Baarda, I.F.; Metzler, D.E. Complexes of riboflavin with silver and other metal ions. In: Biochimica et Biophysica Acta, 1961, vol. 50(3), 463-471, https://doi.org/10.1016/0006-3002(61)90005-1

12. Sheraz, M.A.; Kazi, S.H.; Ahmed S.; Anwar, Z.; Ahmad, I. Photo, thermal and chemical degradation of riboflavin. In: Beilstein J. Org. Chem, 2014, no. 10, 1999-2012, https://doi.org/10.3762/bjoc.10.208

13. Gladchi, V. Transformările catalitice și starea redox a mediului ambiant. Sub red. Acad. Gh. Duca. Chișinău: CEP USM, 2018. 212 p.

Published

2025-11-07

Issue

Section

Articles

Categories

How to Cite

Blonschi, V., Cisteacov, M., Gladchi, V., Bunduchi, E., & Lis, A. (2025). Chemical transformations of vitamin B2 in aquatic systems. Akademos, 3(78), 61-65. https://doi.org/10.52673/18570461.25.3-78.07

Most read articles by the same author(s)